- Hugh Grant Character (Pirate Captain (voice))
- Brendan Gleeson Character (The Pirate with Gout (voice))
- Jeremy Piven Character (Black Bellamy (voice))
- Brian Blessed Character (The Pirate King (voice))
- Salma Hayek Character (Cutlass Liz (voice))
- Imelda Staunton Character (Queen Victoria (voice))
- Ashley Jensen Character (The Surprisingly Curvaceous Pirate (voice))
- David Tennant Character (Charles Darwin (voice))
- Lenny Henry Character (Peg Leg Hastings (voice))
- Martin Freeman Character (The Pirate with a Scarf (voice))
- Russell Tovey Character (The Albino Pirate (voice))
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